Gene description for PTPN11
Gene name protein tyrosine phosphatase non-receptor type 11
Gene symbol PTPN11
Other names/aliases BPTP3
CFC
JMML
METCDS
NS1
PTP-1D
PTP2C
SH-PTP2
SH-PTP3
SHP2
Species Homo sapiens
 Experiment description of studies that identified PTPN11 in Lymphoma cells

1
Experiment ID1669
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34108659   
OrganismHomo sapiens
Experiment descriptionQuantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
AuthorsKugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R.
Journal name Nat Cell Biol
Publication year2021
SampleLymphoma cells
Sample nameRaji
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
mRNA
Methods used in the studyRT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
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